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Clindamycin hydrochloride is a White or practically white, crystalline powder. Freely soluble in water, dimethylformamide and methanol; soluble in alcohol; practically insoluble in acetone.
Specification
Characters White or practically white,crystalline powderIdentification IR Conform
Crystallinity Conform
PH 3.0~5.5 3.9
Water 3.0%~6.0% 4.00%
Related compounds ≤2.0% clindamycin B
≤4.0% 7-epiclindamycin
≤1.0% any other individual related compound
≤6.0% total of all related compound
Residual solvents Acetone ≤5000ppm
Ethanol ≤5000ppm
N,N-Dimethylformamide≤880ppmChloroform≤60ppm
Assay Not less than 800μg of clindamycin (C18H33ClN2O5S)per mg
Application
Clindamycin is used primarily to treat infections caused by susceptible anaerobic bacteria, including infections of the respiratory tract, skin and soft tissue infections, and peritonitis.In patients with hypersensitivity to penicillins, clindamycin may be used to treat infections caused by susceptible aerobic bacteria as well. It is also used to treat bone and joint infections, particularly those caused by Staphylococcus aureus. Topical application of clindamycin phosphate can be used to treat mild to moderate acne.
Packing
25KG/drum
Storage
Stored in a cool and dry well-closed container and in ventilated area, kept away from
moisture and strong light or high temperature.
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