1. Product Information
Product name: Tetramisole Hydrochloride
CAS No.:5086-74-8
EINECS No.: 225-799-5Chemical Formula: C₁₁H₁₂N₂S.HCl
Molecular Weight: 240.75
Synonyms: DL-Tetramisole Hydrochloride, (±)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride
Appearance: White to off‑white crystalline powder, bitter‑astringent taste, odorless
Product Type: Pharmaceutical intermediate, veterinary anthelmintic raw material2. Physical & Chemical Properties
Melting Point 266-267 °C
Solubility Freely soluble in water and methanol; slightly soluble in ethanol; insoluble in acetone
Stability Stable in acidic condition; hydrolyzes under alkaline environment; light-sensitive, keep away from strong alkali and oxidants
3. Quality Specification (Pharmaceutical BPV98 / Industrial Grade)
| Test Item | Specification (Pharma / Industrial Grade) |
|---|---|
| Appearance | White to off‑white crystalline powder |
| Assay (HPLC) | 98.0‑101.0 % |
| Melting point | 266‑267 °C |
| Loss on Drying | ≤0.5 % |
| Residue on Ignition | ≤0.1 % |
| Heavy Metals | ≤10 ppm |
| Related Substances (Total impurities) | ≤1.5 % |
| Single Unknown Impurity | ≤0.5 % |
4. Applications
Pharmaceutical intermediate: Key raw material for producing Levamisole Hydrochloride.
Veterinary field: Broad‑spectrum anthelmintic for nematode infection treatment in animals.
Laboratory reagent: Alkaline phosphatase inhibitor for biochemical research.5. Packaging, Storage & Transportation
- Packaging: 25 kg fiber drum.
- Storage: Keep container tightly closed. Store in cool, dry, dark warehouse. Avoid high temperature, strong light and alkaline substances.
- Transport: Ordinary pharmaceutical solid chemical. Protect from moisture and direct sunlight.
6. Safety Remarks (Refer to SDS for full details)
- May cause irritation to eyes, skin and respiratory tract. Wear chemical-resistant gloves and safety goggles during operation.
- In case of contact, rinse thoroughly with plenty of clean water.
- Suitable fire-extinguishing media: water spray, dry powder, foam, carbon dioxide.
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